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| 產(chǎn)地 | 北京 |
| 保存條件 | -20℃ |
| 品牌 | solarbio |
| 貨號(hào) | P00151 |
| 用途 | 蛋白研究 |
| 組織來源 | 重組 |
| 細(xì)胞形態(tài) | |
| 是否是腫瘤細(xì)胞 | 否 |
| CAS編號(hào) | |
| 保質(zhì)期 | 1年 |
| 器官來源 | |
| 免疫類型 | |
| 品系 | |
| 生長(zhǎng)狀態(tài) | |
| 物種來源 | |
| 包裝規(guī)格 | 10ug |
| 純度 | 95% |
| 是否進(jìn)口 | 否 |
| Known as | High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1 |
|---|---|
| Derived from | E.coli |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 50mMHepes,500mMNaCl,0.5mMDTT, pH7.9 . |
| Shipping | The product is shipped at ambient temperature. |
| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months |
| Reconstitution |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
| Background | High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses. |
| 規(guī)格 | 10ug 50ug 500ug 1mg |
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