| 英文名稱(chēng) | Rabbit MDM2 Polyclonal Antibody |
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| 應(yīng)用2 | WB IHC IF |
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| 克隆類(lèi)型2 | Polyclonal Antibody |
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| 別名 | ACTFS;HDMX;hdm2
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| 應(yīng)用 | WB,IHC,IF |
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| 稀釋比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:200 |
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| 交叉反應(yīng) | Human Mouse Rat |
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| 蛋白分子量 | 55kDa |
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| Gene ID | 4193 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲(chǔ)存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | A synthetic peptide of human MDM2 |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | Q00987 |
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| 克隆類(lèi)型 | Polyclonal Antibody |
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| 來(lái)源 | Rabbit |
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| 背景資料 | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
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