| 英文名稱(chēng) | Rabbit HDAC5 Polyclonal Antibody |
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| 應(yīng)用2 | WB IHC IF |
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| 克隆類(lèi)型2 | Polyclonal Antibody |
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| 別名 | HD5;NY-CO-9
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| 應(yīng)用 | WB,IHC,IF |
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| 稀釋比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:200 |
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| 交叉反應(yīng) | Human Mouse Rat |
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| 蛋白分子量 | 122kDa |
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| Gene ID | 10014 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲(chǔ)存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | A synthetic peptide of human HDAC5 |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | Q9UQL6 |
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| 克隆類(lèi)型 | Polyclonal Antibody |
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| 來(lái)源 | Rabbit |
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| 背景資料 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
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