Anti-c-fos Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-10-29
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K106457P
|
| 應(yīng)用范圍 |
WB IHC
|
| CAS編號 |
|
| 抗體名 |
Anti-c-fos Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點 |
FBLN1
|
| 適應(yīng)物種 |
Human
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標(biāo)識物 |
FOS;G0S7;AP-1;p55
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human c-fos
|
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum
