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北京索萊寶科技有限公司
產(chǎn)品展廳
Anti-CTTN Polyclonal Antibody
  • 品牌:Solarbio
  • 產(chǎn)地:北京
  • 貨號:K107018P
  • 發(fā)布日期: 2019-05-13
  • 更新日期: 2025-10-24
產(chǎn)品詳請
產(chǎn)地 北京
品牌 Solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.
貨號 K107018P
應(yīng)用范圍 WB IHC
CAS編號
抗體名 Anti-CTTN Polyclonal Antibody
克隆性 Polyclonal Antibody
靶點(diǎn)
適應(yīng)物種 Human
形態(tài)
宿主 Rabbit
亞型 IgG
標(biāo)識物 EMS1;cortactin
濃度 %
免疫原 A synthetic peptide of human CTTN
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
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