Anti-PIM1 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-10-24
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K107147P
|
| 應(yīng)用范圍 |
IHC
|
| CAS編號 |
|
| 抗體名 |
Anti-PIM1 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點 |
|
| 適應(yīng)物種 |
Human
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標識物 |
PIM;serine/threonine-protein kinase pim-1
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human PIM1
|
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).
